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What is a Wrinkle Relaxer? What is a wrinkle relaxer? A wrinkle relaxer is an injection that smooths out wrinkles by relaxing the muscle that causes them. Common wrinkle relaxers include Botox, Xeomin, and Dysport. Wrinkle relaxers can treat a variety of areas including, the frown lines, forehead lines, crow’s feet, gummy smiles, lip lines, necklines, the masseter muscle for…